Christina Applegate and Jamie-Lynn Sigler Share How MS ‘Brought Us Together’ — and Inspired Their New Podcast (Exclusive)

Shortly after Christina Applegate received the “devastating” diagnosis that she had multiple sclerosis in June 2021, her friend Lance Bass reached out. “You need to talk to Jamie,” he told her.

Jamie-Lynn Sigler had lived with the disease for two decades, so when Applegate got in touch, The Soprano family the actress, who lives in Austin, was ready to help. “I wanted to give her tools and things that I’ve learned that have helped me,” says Sigler, 42.

Christina Applegate reveals she has been diagnosed with multiple sclerosis

And, says Applegate, “we haven’t stopped talking since.”

Their relationship has since blossomed into a strong friendship that has been a lifesaver for both actresses as they face their futures with the disease. “MS brought us together,” Sigler tells PEOPLE magazine in an exclusive interview with the two actresses next week.

“We have each other and it’s helped us a lot,” says Applegate, 52, who learned she had the disease while filming the final season of her Netflix series. Dead to me.

Now their friendship has inspired a new podcast, MeSsy, which will debut on March 19. “We would talk on the phone for two hours, we would laugh and cry and say: “This is helping us. Let’s record this. Let’s do it,” says Applegate.

Christine Applegate and Jamie-Lynn Sigler’s MeSsy podcast debuts March 19.

Production of wires

Adds Sigler, who hid her own diagnosis for 15 years before revealing it in a 2016 PEOPLE story, “the way Christina disarms me and allows me to talk about difficult things is something I desperately needed.”

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While the podcast (which will also feature conversations with celebrity friends and former colleagues like Martin Short and Edie Falco) provides an unflinching — and darkly humorous — look at the challenges of MS (case in point: the upcoming episode of Adult Diaper Riffs), it’s not a podcast eye MS, they say.

Christina Applegate Tearfully Jokes That Emmys Audience Shouldn’t ‘Applause’ Everything She Does Amid MS Journey

“It’s not about the specific experience we have,” Sigler says. “We’re facing something difficult and that’s figuring out how to push it further. I’ve never been more…nervous isn’t the right word, but like a good anxious about any project I’ve ever started more than this, because I care about it so much. We share the deepest parts of ourselves.”

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Source: HIS Education

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